Mesenteric Lymph Duct Ligation Attenuates Lung Injury and Neutrophil Activation After Intraperitoneal Injection of Endotoxin in Rats

BACKGROUND:The release of injurious factors into the mesenteric lymph from the ischemic intestine has been shown to contribute to lung injury and systemic inflammation after shock and trauma. Since endotoxemia is also associated with gut injury, we tested the hypothesis that mesenteric lymph contrib...

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Veröffentlicht in:	The Journal of trauma, injury, infection, and critical care injury, infection, and critical care, 2008-01, Vol.64 (1), p.126-130
Hauptverfasser:	Watkins, Anthony C., Caputo, Francis J., Badami, Chirag, Barlos, Dimitrios, Xu, Da Zhong, Lu, Qi, Feketeova, Eleanora, Deitch, Edwin A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences CD11b Antigen - metabolism Disease Models, Animal Diseases of the osteoarticular system Endotoxemia - metabolism Escherichia coli General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation Injections, Intraperitoneal Injuries of the limb. Injuries of the spine Ligation Lipopolysaccharides - pharmacology Lung - drug effects Lung - immunology Lung - pathology Lung Diseases - prevention & control Lymphatic Vessels Male Medical sciences Mesentery Neutrophil Activation - drug effects Neutrophil Activation - physiology Neutrophils - immunology Neutrophils - metabolism Permeability - drug effects Rats Rats, Sprague-Dawley Shock - complications Traumas. Diseases due to physical agents
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