Nerve guidance channels as drug delivery vehicles

Nerve guidance channels (NGCs) have been shown to facilitate regeneration after transection injury to the peripheral nerve or spinal cord. Various therapeutic molecules, including neurotrophic factors, have improved regeneration and functional recovery after injury when combined with NGCs; however,...

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Veröffentlicht in:	Biomaterials 2006-03, Vol.27 (9), p.2018-2027
Hauptverfasser:	Piotrowicz, Alexandra, Shoichet, Molly S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Capsules Drug delivery Drug Delivery Systems Drug Implants - chemical synthesis Drug Implants - chemistry HEMA Hydrogel Lactic Acid - chemistry Methylmethacrylates - chemistry Microspheres Nerve Growth Factor - administration & dosage Nerve Growth Factor - chemistry Nerve Growth Factor - pharmacology Nerve guidance channel Nerve Regeneration - drug effects Peripheral Nerves - drug effects Peripheral Nerves - physiology Pharmaceutical Vehicles - chemistry PLGA Polyglycolic Acid - chemistry Polyhydroxyethyl Methacrylate - chemistry Polymers - chemistry Serum Albumin, Bovine - chemistry
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