Aging, peripheral nerve injury and nociception: Effects of the antioxidant 16-desmethyltirilazad

Peripheral neuropathies increase with aging, and reactive oxygen species contribute to the symptomatology of neuropathic pain disorders. In this study, we examined age-related differences in the therapeutic efficacy of pre- or post-treatments of the amino-steroidal antioxidant 16-desmethyltirilazad...

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Veröffentlicht in:	Behavioural brain research 2006-01, Vol.166 (1), p.159-165
Hauptverfasser:	Crisp, Terriann, Minus, Timothy O., Coleman, Michelle L., Giles, Jennifer R., Cibula, Charles, Finnerty, Edward P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - drug effects Aging - physiology Analysis of Variance Animals Antioxidants Antioxidants - therapeutic use Biological and medical sciences Disease Models, Animal Fundamental and applied biological sciences. Psychology Oxidative stress Pain - drug therapy Pain - etiology Pain Measurement - methods Perception Peripheral Nervous System Diseases - prevention & control Persistent nociception Pregnatrienes - therapeutic use Proprioception. Interoception. Pain perception Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred F344 Tactile allodynia Time Factors
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