Recombinant Human Erythropoietin alpha Improves the Efficacy of Radiotherapy of a Human Tumor Xenograft, Affecting Tumor Cells and Microvessels

Background and Purpose: Tumor-induced anemia often occurs in cancer patients, and is corrected by recombinant human erythropoietins (rHuEPOs). Recent studies indicated that, besides erythroid progenitor cells, tumor and endothelial cells express erythropoietin receptor (EPOR) as well; therefore, rHu...

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Veröffentlicht in:	Strahlentherapie und Onkologie 2008, Vol.184 (1), p.1-7
Hauptverfasser:	Lövey, József, Bereczky, Bíborka, Gilly, Réka, Kenessey, István, Rásó, Erzsébet, Simon, Erika, Dobos, Judit, Vágó, Ágnes, Kásler, Miklós, Döme, Balázs, Tímár, József, Tóvári, József
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Apoptosis - radiation effects Cancer Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Cell Division - drug effects Cell Division - radiation effects Cell Line, Tumor Current Discussion Erythropoietin - pharmacology Female Humans Hypoxia In Vitro Techniques Medicine Medicine & Public Health Mice Mice, SCID Neoplasm Transplantation Oncology Radiation therapy Radiation-Sensitizing Agents - pharmacology Radiotherapy Recombinant Proteins Soft Tissue Neoplasms - pathology Soft Tissue Neoplasms - radiotherapy Transplantation, Heterologous Tumor Stem Cell Assay
Online-Zugang:	Volltext
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