Integrative Genomic Analysis of Aneuploidy in Uveal Melanoma

Purpose: Aneuploidy is a hallmark of cancer and is closely linked to metastasis and poor clinical outcome. Yet, the mechanisms leading to aneuploidy and its role in tumor progression remain poorly understood. The extensive and complex karyotypic abnormalities seen in many solid tumors could hinder t...

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Veröffentlicht in:Clinical cancer research 2008-01, Vol.14 (1), p.115-122
Hauptverfasser: EHLERS, Justis P, WORLEY, Lori, ONKEN, Michael D, HARBOUR, J. William
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Sprache:eng
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