Photosensitizing and Radiosensitizing Effects of Hypericin on Human Renal Carcinoma Cells in Vitro

The renal cell carcinoma (RCC) is extremely resistant to chemotherapy and radiotherapy. The prognosis of patients with metastatic RCC still remains poor, the median survival is less than 12 months. Therefore, new therapeutic options are desirable. The aim of this study was to investigate the photose...

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Veröffentlicht in:	Photochemistry and photobiology 2008-01, Vol.84 (1), p.228-235
Hauptverfasser:	Wessels, Johannes Theodor, Busse, Ann-Christin, Rave-Fränk, Margret, Zänker, Stephan, Hermann, Robert, Grabbe, Eckhardt, Müller, Gerhard-Anton
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Cell Line, Tumor Cell Survival - drug effects Humans Kinases Perylene - analogs & derivatives Perylene - pharmacology Photodynamic therapy Photosensitizing Agents - pharmacology Radiation therapy
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