Rab proteins in endocytosis and Glut4 trafficking

The intracellular trafficking of numerous proteins requires a tight control to fulfil their physiological functions. It is the case of the adipocyte and muscle glucose transporter Glut4 that is retained intracellularly until insulin induces its recruitment to the plasma membrane. Rabs are evolutiona...

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Veröffentlicht in:	Acta Physiologica 2008-01, Vol.192 (1), p.75-88
Hauptverfasser:	Kaddai, V., Le Marchand-Brustel, Y., Cormont, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	adipocyte Animals Biological and medical sciences Cytoplasmic Vesicles - metabolism Endocytosis - physiology endosomes Fundamental and applied biological sciences. Psychology Glucose Transporter Type 4 - metabolism Humans insulin Insulin - physiology muscle Protein Transport - physiology Rab effectors rab GTP-Binding Proteins - physiology RabGAP RabGEF Signal Transduction - physiology Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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