Pancreatic stellate cells: New target in the treatment of chronic pancreatitis

Chronic pancreatitis (CP) is characterized by progressive fibrosis, pain and/or loss of exocrine and endocrine functions. Recent in vitro and in vivo experiments have proven objectively the role of activated pancreatic stellate cells (PSC) in fibrogenesis in CP. Molecular mediators shown to regulate...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2008-01, Vol.23 (1), p.34-41
Hauptverfasser:	Talukdar, Rupjyoti, Tandon, Rakesh K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Biological and medical sciences Cells - drug effects Cells - pathology chronic pancreatitis Disease Models, Animal fibrosis Gastroenterology. Liver. Pancreas. Abdomen Humans interleukin Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences newer therapeutic agents Other diseases. Semiology Pancreas - pathology pancreatic stellate cells Pancreatitis, Chronic - drug therapy Pancreatitis, Chronic - pathology platelet-derived growth factor Rats transforming growth factor beta tumor necrosis factor alpha
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