Molecular inversion probes for sensitive detection of Mycobacterium tuberculosis

Nucleic acid-based detection of Mycobacterium tuberculosis infections has the potential to improve the analysis of the tuberculosis epidemiology and patient care by increasing the specificity and sensitivity of diagnosis. One potential diagnostic sequence, the DR locus, is present in all isolates of...

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Veröffentlicht in:	Journal of microbiological methods 2008, Vol.72 (1), p.60-66
Hauptverfasser:	Novais, Rogerio C., Borsuk, Sibelle, Dellagostin, Odir A., Thorstenson, Yvonne R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Typing Techniques Base Sequence Biological and medical sciences Diphosphates - metabolism DNA, Bacterial - analysis DNA, Bacterial - isolation & purification Fundamental and applied biological sciences. Psychology Humans Inorganic Chemicals - metabolism Microbiology Molecular inversion probes Molecular Probe Techniques Molecular Probes Molecular Sequence Data Mycobacterium tuberculosis Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Oligonucleotides - genetics Pyrosequencing Repetitive Sequences, Nucleic Acid - genetics Sensitivity and Specificity Sequence Analysis, DNA - methods Tuberculosis Tuberculosis - diagnosis Tuberculosis - microbiology
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