An Actinobacillus pleuropneumoniae arcA deletion mutant is attenuated and deficient in biofilm formation

Actinobacillus pleuropneumoniae is a facultative anaerobic pathogen of the porcine respiratory tract requiring anaerobic metabolic activity for persistence on lung epithelium. The ArcAB two-component system facilitating metabolic adaptation to anaerobicity was investigated with regard to its impact...

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Veröffentlicht in:	Veterinary microbiology 2008-02, Vol.127 (1), p.106-115
Hauptverfasser:	Buettner, Falk F.R., Maas, Alexander, Gerlach, Gerald-F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacillus Infections - microbiology Actinobacillus Infections - veterinary Actinobacillus pleuropneumoniae Actinobacillus pleuropneumoniae - genetics Actinobacillus pleuropneumoniae - growth & development Actinobacillus pleuropneumoniae - isolation & purification Actinobacillus pleuropneumoniae - pathogenicity anaerobic conditions animal pathogenic bacteria Animals Arca ArcAB two-component system bacterial colonization bacterial infections Bacterial Outer Membrane Proteins - genetics Bacteriology Biofilm Biofilms - growth & development Biological and medical sciences cell aggregates DNA Mutational Analysis - methods epithelium Fundamental and applied biological sciences. Psychology gene deletion genes lungs microbial growth Microbiology Microscopy, Electron Miscellaneous mutants Sequence Deletion - genetics Survival Analysis Swine swine diseases Swine Diseases - microbiology Time Factors Virulence Virulence - genetics
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