Ramipril protects from free radical induced white matter damage in chronic hypoperfusion in the rat

Abstract We investigated whether the angiotensin converting enzyme inhibitor, ramipril, could attenuate white matter lesions caused by chronic hypoperfusion in the rat, and whether suppression of oxidative stress is involved in the resulting neuroprotection. The ramipril treatment group showed signi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical neuroscience 2008-02, Vol.15 (2), p.174-178
Hauptverfasser:	Kim, Joong-Seok, Yun, Injin, Choi, Young Bin, Lee, Kwang-Soo, Kim, Yeong-In
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Brain Injuries - etiology Brain Injuries - pathology Brain Injuries - prevention & control Brain Ischemia - complications Chronic cerebral hypoperfusion Chronic Disease Disease Models, Animal Free radical Free Radicals - metabolism Glutathione - metabolism Glutathione Disulfide - metabolism Malondialdehyde - metabolism Neuroglia - drug effects Neuroglia - pathology Neurology Ramipril Ramipril - therapeutic use Rat Rats Rats, Sprague-Dawley Scavenger
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!