Artificial cells: building bioinspired systems using small-scale biology

Artificial cells have generated much interest since the concept was introduced by Aleksandr Oparin in the 1920s, and they have had an impact on the pharmaceutical and biotechnology industry in various areas, including potential therapeutic applications. Here, we discuss the development of small-scal...

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Veröffentlicht in:Trends in biotechnology (Regular ed.) 2008-01, Vol.26 (1), p.14-20
Hauptverfasser: Zhang, Ying, Ruder, Warren C, LeDuc, Philip R
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container_title Trends in biotechnology (Regular ed.)
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creator Zhang, Ying
Ruder, Warren C
LeDuc, Philip R
description Artificial cells have generated much interest since the concept was introduced by Aleksandr Oparin in the 1920s, and they have had an impact on the pharmaceutical and biotechnology industry in various areas, including potential therapeutic applications. Here, we discuss the development of small-scale, bio-inspired artificial cell components that recreate the function of key cellular and physiological systems. We describe artificial cells, selected current applications and how small-scale biology could be used to provide what might be a next-generation approach in this area. We believe that this type of work is in its infancy and that exploiting small-scale biological inspiration in the field of artificial cells has great potential for successes in the future.
doi_str_mv 10.1016/j.tibtech.2007.09.006
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subjects Aqueous solutions
Biological and medical sciences
Biological Transport
Biology - methods
Biotechnology
Blood-brain barrier
Cell Culture Techniques - methods
Cell Survival
Drug Delivery Systems
Enzymes
Fundamental and applied biological sciences. Psychology
Health. Pharmaceutical industry
Immune system
Industrial applications and implications. Economical aspects
Internal Medicine
Miscellaneous
Nanotechnology
Proteins
Quantum dots
Rodents
Studies
Technological change
title Artificial cells: building bioinspired systems using small-scale biology
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