The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma

Matrix metalloproteinase-2 (MMP-2) and its inhibitor, tissue inhibitor of matrix metalloproteinase 2 (TIMP2), are known to be important in cancer. The purposes of this study were to determine the cDNA sequence of canine MMP-2 and to investigate the expression patterns of MMP-2 and TIMP2 in normal ca...

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Veröffentlicht in:	Research in veterinary science 2008-04, Vol.84 (2), p.206-214
Hauptverfasser:	Newman, R.G., Kitchell, B.E., Wallig, M.A., Paria, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence amino acid sequences Animals Base Sequence Binding sites Canine carcinogenesis Cloning Cloning, Molecular complementary DNA DNA fingerprinting Dog dog diseases Dogs gene expression Gene Expression Regulation genes Health histopathology inhibitors lymph nodes Lymph Nodes - enzymology Lymphocytes Lymphoma Lymphoma - enzymology Matrix metalloproteinase 2 Matrix Metalloproteinase 2 - chemistry Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - metabolism metalloproteinases molecular cloning molecular genetics Molecular Sequence Data phenotype Plasmids protein synthesis sequence analysis Studies TIMP2 tissue inhibitor of matrix metalloproteinase-2 Tissue Inhibitor of Metalloproteinase-2 - genetics Tissue Inhibitor of Metalloproteinase-2 - metabolism Veterinary medicine Wound healing
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