Estradiol/progesterone implants increase food intake, reduce hyperglycemia and increase insulin resistance in endotoxic steers

High doses of lipopolysaccharide (LPS) induce transient hyperglycemia, then chronic hypoglycemia and increased insulin resistance. In addition, appetite is reduced, while body temperature and concentrations of cortisol and tumor necrosis factor alpha (TNFalpha) are elevated. Furthermore, concentrati...

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Veröffentlicht in:	Journal of endocrinology 1998-12, Vol.159 (3), p.469-478
Hauptverfasser:	McMahon, CD, Elsasser, TH, Gunter, DR, Sanders, LG, Steele, BP, Sartin, JL
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Glucose - metabolism Blood Urea Nitrogen Cattle Cattle Diseases - drug therapy Cattle Diseases - metabolism Drug Implants Drug Therapy, Combination Eating - drug effects Endotoxemia - drug therapy Endotoxemia - metabolism Endotoxemia - veterinary Estradiol - therapeutic use Fatty Acids, Nonesterified - blood Fever - drug therapy Fever - metabolism General aspects Growth Hormone - blood Human infectious diseases. Experimental studies and models Hydrocortisone - blood Infectious diseases Insulin Resistance Insulin-Like Growth Factor I - metabolism Least-Squares Analysis Male Medical sciences Progesterone - therapeutic use Time Factors Tumor Necrosis Factor-alpha - analysis
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