Characterization of immunogenic properties of polyclonal T cell vaccine intended for the treatment of rheumatoid arthritis

Two-staged technology for obtaining polyclonal T cell vaccine intended for the treatment of rheumatoid arthritis is described. Stage 1 includes antigen-dependent cultural selection of patient's T cells and stage 2 consists in their reproduction in the needed amounts by nonspecific mitogenic sti...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2007-10, Vol.144 (4), p.630-634
Hauptverfasser:	Ivanova, I P, Seledtsov, V I, Seledtsov, D V, Samarin, D M, Seledtsova, G V, Herzsog, O A, Kozlov, V A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer - methods Adult Aged Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - therapy Female Humans Interferon-gamma - blood Interferon-gamma - immunology Interleukin-4 - blood Interleukin-4 - immunology Joint Diseases - blood Joint Diseases - immunology Joint Diseases - therapy Middle Aged T-Lymphocytes - immunology T-Lymphocytes - transplantation Treatment Outcome Vaccines - immunology
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