Molecular characterization of woodchuck interleukin 15 (wIL-15) and detection of its expression in liver samples of woodchucks infected with woodchuck hepatitis virus (WHV)

Interleukin 15 (IL-15) is a member of the four-helix bundle cytokine family and has T cell growth factor activity. IL-15 plays a unique role in both innate and adaptive immune cell homeostasis, particularly for the development of NK cells and CD8 + memory cells. It may be useful for stimulation of s...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2005-12, Vol.32 (6), p.296-303
Hauptverfasser:	Wang, Baoju, Lohrengel, Beate, Lu, Yinping, Meng, Zhongji, Xu, Yang, Yang, Dongliang, Roggendorf, Micheal, Lu, Mengji
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Blotting, Western Cell Proliferation - drug effects Cloning, Molecular Concanavalin A - pharmacology DNA, Complementary - chemistry DNA, Complementary - genetics Escherichia coli - genetics Gene Expression - genetics Hepadnavirus Hepatitis B - genetics Hepatitis B - metabolism Hepatitis B - virology Hepatitis B virus Hepatitis B Virus, Woodchuck Interleukin-15 Interleukin-15 - biosynthesis Interleukin-15 - genetics Interleukin-15 - pharmacology Intrahepatic expression Leukocytes, Mononuclear - chemistry Leukocytes, Mononuclear - drug effects Liver - metabolism Liver - virology Lymphocyte Activation - drug effects Marmota - genetics Marmota - virology Molecular Sequence Data Recombinant Proteins - biosynthesis Recombinant Proteins - isolation & purification Recombinant Proteins - pharmacology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Analysis, DNA Sequence Homology, Amino Acid Spleen - cytology Woodchuck Woodchuck hepatitis virus
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