Regulation of insulin-like growth factor-binding protein-3 ternary complex formation in pregnancy

The IGFs are believed to be important in pregnancy and are implicated in the pathophysiology of pre-eclampsia. In adults the IGFs circulate primarily with IGF-binding protein-3 (IGFBP-3) and an acid-labile glycoprotein (ALS) in a 140 kDa complex which limits IGF bioavailability. Less than 10% of IGF...

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Veröffentlicht in:	Journal of endocrinology 1998-11, Vol.159 (2), p.265-274
Hauptverfasser:	Lewitt, MS, Scott, FP, Clarke, NM, Wu, T, Sinosich, MJ, Baxter, RC
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amniotic Fluid - chemistry Analysis of Variance Biological and medical sciences Chromatography, Gel Diseases of mother, fetus and pregnancy Female Fetal Blood - chemistry Gestational Age Glycoprotein Hormones, alpha Subunit - blood Gynecology. Andrology. Obstetrics Humans Insulin-Like Growth Factor Binding Protein 1 - blood Insulin-Like Growth Factor Binding Protein 2 - blood Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor Binding Protein 3 - metabolism Insulin-Like Growth Factor Binding Protein 6 - blood Insulin-Like Growth Factor I - analysis Insulin-Like Growth Factor II - analysis Medical sciences Molecular Weight Pre-Eclampsia - blood Pre-Eclampsia - metabolism Pregnancy Pregnancy. Fetus. Placenta
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