Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis

Asthma and chronic bronchitis are inflammatory diseases with extracellular matrix (ECM) remodeling and collagen deposition. Collagen homeostasis is controlled by metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). We evaluated MMP and TIMP balance in induced sputum of 10 c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of respiratory and critical care medicine 1998-12, Vol.158 (6), p.1945-1950
Hauptverfasser:	VIGNOLA, A. M, RICCOBONO, L, MIRABELLA, A, PROFITA, M, CHANEZ, P, BELLIA, V, MAUTINO, G, DACCARDI, P, BOUSQUET, J, BONSIGNORE, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Airway Obstruction - enzymology Airway Obstruction - metabolism Airway Obstruction - pathology Airway Obstruction - physiopathology Asthma - enzymology Asthma - metabolism Asthma - pathology Asthma - physiopathology Biological and medical sciences Bronchitis - enzymology Bronchitis - metabolism Bronchitis - pathology Bronchitis - physiopathology Cell Count Chronic Disease Chronic obstructive pulmonary disease, asthma Collagen - metabolism Collagenases - analysis Electrophoresis, Polyacrylamide Gel Enzyme-Linked Immunosorbent Assay Extracellular Matrix - metabolism Forced Expiratory Volume - physiology Homeostasis - physiology Humans Leukocyte Count Macrophages - pathology Matrix Metalloproteinase 9 Medical sciences Middle Aged Neutrophils - pathology Pneumology Protease Inhibitors - analysis Pulmonary Ventilation - physiology Sodium Dodecyl Sulfate Sputum - chemistry Sputum - cytology Sputum - enzymology Surface-Active Agents Tissue Inhibitor of Metalloproteinase-1 - analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!