Cytological evaluation and investigation of the vaginal flora of long-term users of the levonorgestrel-releasing intrauterine system (LNG-IUS)
Abstract Background The study was conducted to evaluate the cytopathological findings and vaginal flora in cervical smear samples from women using the levonorgestrel-releasing intrauterine system (LNG-IUS) for a period of up to 7 years. Study Design Postinsertion cytology examinations were conducted...
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| Veröffentlicht in: | Contraception (Stoneham) 2008-01, Vol.77 (1), p.30-33 |
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| creator | Lessard, Trícia Simões, José A Discacciati, Michelle G Hidalgo, Margarete Bahamondes, Luis |
| description | Abstract Background The study was conducted to evaluate the cytopathological findings and vaginal flora in cervical smear samples from women using the levonorgestrel-releasing intrauterine system (LNG-IUS) for a period of up to 7 years. Study Design Postinsertion cytology examinations were conducted on 187 women who had an LNG-IUS inserted between April and September 1998 in the family planning clinic of the Universidade Estadual de Campinas. Results During the 7 years of follow-up, a high frequency of candidiasis was found from the fourth through the seventh year of use in comparison to the first year of use. No significant results were found with respect to cytopathological abnormalities or other microbiological alterations following insertion of the LNG-IUS. Conclusion Use of the LNG-IUS had no effect on cervical smears over the 7-year follow-up period; however, an increase occurred in the frequency of candidiasis. |
| doi_str_mv | 10.1016/j.contraception.2007.09.009 |
| format | Article |
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Study Design Postinsertion cytology examinations were conducted on 187 women who had an LNG-IUS inserted between April and September 1998 in the family planning clinic of the Universidade Estadual de Campinas. Results During the 7 years of follow-up, a high frequency of candidiasis was found from the fourth through the seventh year of use in comparison to the first year of use. No significant results were found with respect to cytopathological abnormalities or other microbiological alterations following insertion of the LNG-IUS. Conclusion Use of the LNG-IUS had no effect on cervical smears over the 7-year follow-up period; however, an increase occurred in the frequency of candidiasis.</description><identifier>ISSN: 0010-7824</identifier><identifier>EISSN: 1879-0518</identifier><identifier>DOI: 10.1016/j.contraception.2007.09.009</identifier><identifier>PMID: 18082663</identifier><identifier>CODEN: CCPTAY</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Birth control ; Brazil ; Candidiasis ; Cervix Uteri - cytology ; Contraceptive Agents, Female - administration & dosage ; Cytopathological abnormalities ; Female ; Follow-Up Studies ; Genital system. Reproduction ; Gynecology. Andrology. Obstetrics ; Humans ; Intrauterine Devices, Medicated - microbiology ; Levonorgestrel - administration & dosage ; LNG-IUS ; Longitudinal Studies ; Medical sciences ; Microbiological abnormalities ; Obstetrics and Gynecology ; Other methods of contraception. Sterilization ; Papanicolaou ; Pharmacology. Drug treatments ; Vagina - microbiology ; Vaginal flora ; Vaginal Smears ; Vaginitis</subject><ispartof>Contraception (Stoneham), 2008-01, Vol.77 (1), p.30-33</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-aa7dc2e0b06ee66597a847a9051eeb1bd3edba26a007f1c1543865ad1b8bcf63</citedby><cites>FETCH-LOGICAL-c491t-aa7dc2e0b06ee66597a847a9051eeb1bd3edba26a007f1c1543865ad1b8bcf63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.contraception.2007.09.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19949999$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18082663$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lessard, Trícia</creatorcontrib><creatorcontrib>Simões, José A</creatorcontrib><creatorcontrib>Discacciati, Michelle G</creatorcontrib><creatorcontrib>Hidalgo, Margarete</creatorcontrib><creatorcontrib>Bahamondes, Luis</creatorcontrib><title>Cytological evaluation and investigation of the vaginal flora of long-term users of the levonorgestrel-releasing intrauterine system (LNG-IUS)</title><title>Contraception (Stoneham)</title><addtitle>Contraception</addtitle><description>Abstract Background The study was conducted to evaluate the cytopathological findings and vaginal flora in cervical smear samples from women using the levonorgestrel-releasing intrauterine system (LNG-IUS) for a period of up to 7 years. Study Design Postinsertion cytology examinations were conducted on 187 women who had an LNG-IUS inserted between April and September 1998 in the family planning clinic of the Universidade Estadual de Campinas. Results During the 7 years of follow-up, a high frequency of candidiasis was found from the fourth through the seventh year of use in comparison to the first year of use. No significant results were found with respect to cytopathological abnormalities or other microbiological alterations following insertion of the LNG-IUS. Conclusion Use of the LNG-IUS had no effect on cervical smears over the 7-year follow-up period; however, an increase occurred in the frequency of candidiasis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Brazil</subject><subject>Candidiasis</subject><subject>Cervix Uteri - cytology</subject><subject>Contraceptive Agents, Female - administration & dosage</subject><subject>Cytopathological abnormalities</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Genital system. Reproduction</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Intrauterine Devices, Medicated - microbiology</subject><subject>Levonorgestrel - administration & dosage</subject><subject>LNG-IUS</subject><subject>Longitudinal Studies</subject><subject>Medical sciences</subject><subject>Microbiological abnormalities</subject><subject>Obstetrics and Gynecology</subject><subject>Other methods of contraception. Sterilization</subject><subject>Papanicolaou</subject><subject>Pharmacology. Drug treatments</subject><subject>Vagina - microbiology</subject><subject>Vaginal flora</subject><subject>Vaginal Smears</subject><subject>Vaginitis</subject><issn>0010-7824</issn><issn>1879-0518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkm-L1DAQxoso3nr6FaQgir5onfR_EARZzvNg0Rd3vg5pOq1Z02QvaQv7JfzMTtmVQ18ZCIHhN09m5pkoesUgZcCq9_tUOTt5qfAwaWfTDKBOgacA_FG0YU3NEyhZ8zjaADBI6iYrLqJnIeyBQF7WT6ML1kCTVVW-iX5tj5MzbtBKmhgXaWa5isbSdrG2C4ZJD6eI6-PpB8aLHLQltjfOyzVonB2SCf0YzwF9-MMZXJx1fiAFjyahizJoO5Aq1T5TgrYYh2OYcIzf7r5eJzffb989j5700gR8cX4vo7vPV3fbL8nu2_XN9tMuUQVnUyJl3akMoYUKsapKXsumqCWnvhFb1nY5dq3MKkkd90yxssibqpQda5tW9VV-Gb05yR68u5-pRDHqoNAYadHNQdTA6GQZgR9OoPIuBI-9OHg9Sn8UDMTqhtiLv9wQqxsCuCA3KPvl-Zu5HbF7yD2Pn4DXZ0AGMqD30iodHjjOC06HuKsThzSTRaMXQWm0CjvtUU2ic_o_C_r4j44y2q7e_8Qjhr2bPXkbBBMhEyBu1wVa9wdqgCIrm_w3IHzJHg</recordid><startdate>20080101</startdate><enddate>20080101</enddate><creator>Lessard, Trícia</creator><creator>Simões, José A</creator><creator>Discacciati, Michelle G</creator><creator>Hidalgo, Margarete</creator><creator>Bahamondes, Luis</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080101</creationdate><title>Cytological evaluation and investigation of the vaginal flora of long-term users of the levonorgestrel-releasing intrauterine system (LNG-IUS)</title><author>Lessard, Trícia ; Simões, José A ; Discacciati, Michelle G ; Hidalgo, Margarete ; Bahamondes, Luis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-aa7dc2e0b06ee66597a847a9051eeb1bd3edba26a007f1c1543865ad1b8bcf63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Brazil</topic><topic>Candidiasis</topic><topic>Cervix Uteri - cytology</topic><topic>Contraceptive Agents, Female - administration & dosage</topic><topic>Cytopathological abnormalities</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Genital system. Reproduction</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Intrauterine Devices, Medicated - microbiology</topic><topic>Levonorgestrel - administration & dosage</topic><topic>LNG-IUS</topic><topic>Longitudinal Studies</topic><topic>Medical sciences</topic><topic>Microbiological abnormalities</topic><topic>Obstetrics and Gynecology</topic><topic>Other methods of contraception. Sterilization</topic><topic>Papanicolaou</topic><topic>Pharmacology. Drug treatments</topic><topic>Vagina - microbiology</topic><topic>Vaginal flora</topic><topic>Vaginal Smears</topic><topic>Vaginitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lessard, Trícia</creatorcontrib><creatorcontrib>Simões, José A</creatorcontrib><creatorcontrib>Discacciati, Michelle G</creatorcontrib><creatorcontrib>Hidalgo, Margarete</creatorcontrib><creatorcontrib>Bahamondes, Luis</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Contraception (Stoneham)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lessard, Trícia</au><au>Simões, José A</au><au>Discacciati, Michelle G</au><au>Hidalgo, Margarete</au><au>Bahamondes, Luis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytological evaluation and investigation of the vaginal flora of long-term users of the levonorgestrel-releasing intrauterine system (LNG-IUS)</atitle><jtitle>Contraception (Stoneham)</jtitle><addtitle>Contraception</addtitle><date>2008-01-01</date><risdate>2008</risdate><volume>77</volume><issue>1</issue><spage>30</spage><epage>33</epage><pages>30-33</pages><issn>0010-7824</issn><eissn>1879-0518</eissn><coden>CCPTAY</coden><abstract>Abstract Background The study was conducted to evaluate the cytopathological findings and vaginal flora in cervical smear samples from women using the levonorgestrel-releasing intrauterine system (LNG-IUS) for a period of up to 7 years. Study Design Postinsertion cytology examinations were conducted on 187 women who had an LNG-IUS inserted between April and September 1998 in the family planning clinic of the Universidade Estadual de Campinas. Results During the 7 years of follow-up, a high frequency of candidiasis was found from the fourth through the seventh year of use in comparison to the first year of use. No significant results were found with respect to cytopathological abnormalities or other microbiological alterations following insertion of the LNG-IUS. Conclusion Use of the LNG-IUS had no effect on cervical smears over the 7-year follow-up period; however, an increase occurred in the frequency of candidiasis.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18082663</pmid><doi>10.1016/j.contraception.2007.09.009</doi><tpages>4</tpages></addata></record> |
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| subjects | Adolescent Adult Biological and medical sciences Birth control Brazil Candidiasis Cervix Uteri - cytology Contraceptive Agents, Female - administration & dosage Cytopathological abnormalities Female Follow-Up Studies Genital system. Reproduction Gynecology. Andrology. Obstetrics Humans Intrauterine Devices, Medicated - microbiology Levonorgestrel - administration & dosage LNG-IUS Longitudinal Studies Medical sciences Microbiological abnormalities Obstetrics and Gynecology Other methods of contraception. Sterilization Papanicolaou Pharmacology. Drug treatments Vagina - microbiology Vaginal flora Vaginal Smears Vaginitis |
| title | Cytological evaluation and investigation of the vaginal flora of long-term users of the levonorgestrel-releasing intrauterine system (LNG-IUS) |
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