Striatal Dopamine Synthesis in First-degree Relatives of Patients with Schizophrenia

Background First degree relatives (FDR) of patients with schizophrenia have higher risk of developing schizophrenia than the general population. Previous positron emission tomography (PET) studies have shown that striatal presynaptic dopamine synthesis capacity is increased in schizophrenia. We inve...

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Veröffentlicht in:	Biological psychiatry (1969) 2008, Vol.63 (1), p.114-117
Hauptverfasser:	Huttunen, Jukka, Heinimaa, Markus, Svirskis, Tanja, Nyman, Mikko, Kajander, Jaana, Forsback, Sarita, Solin, Olof, Ilonen, Tuula, Korkeila, Jyrki, Ristkari, Terja, McGlashan, Thomas, Salokangas, Raimo K.R, Hietala, Jarmo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Analysis of Variance Biological and medical sciences Corpus Striatum - diagnostic imaging Corpus Striatum - metabolism Dihydroxyphenylalanine - metabolism Dopamine - metabolism Dopamine receptors early detection Female first degree relatives Fluorine Radioisotopes - metabolism genetics positron emission tomography Humans Male Medical sciences Positron-Emission Tomography - methods Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Retrospective Studies Schizophrenia Schizophrenia - diagnostic imaging Schizophrenia - enzymology Schizophrenia - pathology
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