Outcome of retinoblastoma in east Africa
We estimated the proportion of patients reaching a pediatric ophthalmology unit (Comprehensive Community Based Rehabilitation for Tanzania Disability Hospital, CCBRT) or an oncology unit (ORCI) in east Africa and investigated presentation, histology, and treatment outcomes of patients with retinobla...
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| Veröffentlicht in: | Pediatric blood & cancer 2008-01, Vol.50 (1), p.160-162 |
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| container_title | Pediatric blood & cancer |
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| creator | Bowman, R.J.C. Mafwiri, M. Luthert, P. Luande, J. Wood, M. |
| description | We estimated the proportion of patients reaching a pediatric ophthalmology unit (Comprehensive Community Based Rehabilitation for Tanzania Disability Hospital, CCBRT) or an oncology unit (ORCI) in east Africa and investigated presentation, histology, and treatment outcomes of patients with retinoblastoma. A 5‐year retrospective study identified 91 patients, representing approximately 18% of the nationwide total. Mean lag time was 10 months (standard deviation (SD) = 17) and mean follow‐up was 8 months (SD = 11, range 0–40, n = 91). Thirty months disease‐free survival probability was 0.23 (standard error = 0.07). Outcomes for retinoblastoma in Africa remain poor. The data presented here suggest strategies for improving the outcomes, including encouraging earlier presentation and establishment of multi‐disciplinary treatment centers. Pediatr Blood Cancer 2008;50:160–162. © 2006 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/pbc.21080 |
| format | Article |
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Blood Cancer</addtitle><description>We estimated the proportion of patients reaching a pediatric ophthalmology unit (Comprehensive Community Based Rehabilitation for Tanzania Disability Hospital, CCBRT) or an oncology unit (ORCI) in east Africa and investigated presentation, histology, and treatment outcomes of patients with retinoblastoma. A 5‐year retrospective study identified 91 patients, representing approximately 18% of the nationwide total. Mean lag time was 10 months (standard deviation (SD) = 17) and mean follow‐up was 8 months (SD = 11, range 0–40, n = 91). Thirty months disease‐free survival probability was 0.23 (standard error = 0.07). Outcomes for retinoblastoma in Africa remain poor. The data presented here suggest strategies for improving the outcomes, including encouraging earlier presentation and establishment of multi‐disciplinary treatment centers. Pediatr Blood Cancer 2008;50:160–162. © 2006 Wiley‐Liss, Inc.</description><subject>Africa</subject><subject>Child, Preschool</subject><subject>Disease-Free Survival</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>outcome</subject><subject>Retinal Neoplasms - epidemiology</subject><subject>Retinal Neoplasms - surgery</subject><subject>retinoblastoma</subject><subject>Retinoblastoma - epidemiology</subject><subject>Retinoblastoma - surgery</subject><subject>Tanzania - epidemiology</subject><issn>1545-5009</issn><issn>1545-5017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kF1LwzAUhoMobk4v_APSK9GLbknz1VzOoVMYTsZk4E1I0xSq7TKTFt2_N9o5r7w6B87zvnAeAM4RHCIIk9Em08MEwRQegD6ihMYUIn6436HogRPvXwPKIE2PQQ9xlMCEoD64mreNtrWJbBE505Rrm1XKN7ZWUbmOTFijceFKrU7BUaEqb852cwCe726Xk_t4Np8-TMazWGPBYJxwQlUqkMhZRgVSNFcF4QwiQikRKGM8z3GhONYsI9AwonPCc5aGiyY6SfEAXHa9G2ffW-MbWZdem6pSa2NbLzkMj3LBAnjdgdpZ750p5MaVtXJbiaD81iKDFvmjJbAXu9I2q03-R-48BGDUAR9lZbb_N8mnm8lvZdwlSt-Yz31CuTfJOOZUrh6ncrVcvKAFxjLFX3LMeIA</recordid><startdate>200801</startdate><enddate>200801</enddate><creator>Bowman, R.J.C.</creator><creator>Mafwiri, M.</creator><creator>Luthert, P.</creator><creator>Luande, J.</creator><creator>Wood, M.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200801</creationdate><title>Outcome of retinoblastoma in east Africa</title><author>Bowman, R.J.C. ; Mafwiri, M. ; Luthert, P. ; Luande, J. ; Wood, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3960-2745a8919d6b591a5daf47601455491b67dd3fa73c6b40e64cd47d681b6c4c283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Africa</topic><topic>Child, Preschool</topic><topic>Disease-Free Survival</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>outcome</topic><topic>Retinal Neoplasms - epidemiology</topic><topic>Retinal Neoplasms - surgery</topic><topic>retinoblastoma</topic><topic>Retinoblastoma - epidemiology</topic><topic>Retinoblastoma - surgery</topic><topic>Tanzania - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bowman, R.J.C.</creatorcontrib><creatorcontrib>Mafwiri, M.</creatorcontrib><creatorcontrib>Luthert, P.</creatorcontrib><creatorcontrib>Luande, J.</creatorcontrib><creatorcontrib>Wood, M.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric blood & cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bowman, R.J.C.</au><au>Mafwiri, M.</au><au>Luthert, P.</au><au>Luande, J.</au><au>Wood, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcome of retinoblastoma in east Africa</atitle><jtitle>Pediatric blood & cancer</jtitle><addtitle>Pediatr. 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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Africa Child, Preschool Disease-Free Survival Female Humans Incidence Male outcome Retinal Neoplasms - epidemiology Retinal Neoplasms - surgery retinoblastoma Retinoblastoma - epidemiology Retinoblastoma - surgery Tanzania - epidemiology |
| title | Outcome of retinoblastoma in east Africa |
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