Treatment of Pediatric non-Hodgkin lymphomas in a country with limited resources: Results of the first national protocol in Nicaragua

We report the results of a protocol for the diagnosis and treatment of pediatric non‐Hodgkin lymphomas (NHL) conducted in Nicaragua in the context of an international collaborative program. Fifty‐three children with NHL treated between 1996 and 2003 were retrospectively evaluated. Therapy was design...

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Veröffentlicht in:Pediatric Blood & Cancer 2008-01, Vol.50 (1), p.148-152
Hauptverfasser: Baez, F., Pillon, M., Manfredini, L., Ocampo, E., Mendez, G., Ortiz, R., Palacios, R., Gutierrez, T., Tridello, G., Conter, V., Valsecchi, MG, Bellani, F. Fossati, Cavalli, F., Masera, G., Rosolen, A.
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Sprache:eng
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Zusammenfassung:We report the results of a protocol for the diagnosis and treatment of pediatric non‐Hodgkin lymphomas (NHL) conducted in Nicaragua in the context of an international collaborative program. Fifty‐three children with NHL treated between 1996 and 2003 were retrospectively evaluated. Therapy was designed based on local drug availability and affordability with dose and schedule adaptations for Burkitt and lymphoblastic lymphomas. With a median follow‐up of 3 years, the projected 9‐year overall survival was 63% and event‐free survival 53%. The treatment was efficacious, feasible, and well tolerated in spite of the local socio‐economical conditions. Pediatr Blood Cancer 2008;50:148–152. © 2006 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
1096-911X
DOI:10.1002/pbc.21046