In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development
The compliance of the bladder which accommodates the holding and voiding of urine is influenced by the amount and type of collagen deposited as well as the packing and organization of collagen fiber bundles. During fetal development, the accumulation of urine within the bladder lumen is associated w...
Gespeichert in:
Veröffentlicht in: | Tissue & cell 1998-10, Vol.30 (5), p.531-536 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 536 |
---|---|
container_issue | 5 |
container_start_page | 531 |
container_title | Tissue & cell |
container_volume | 30 |
creator | Beauboeuf, Andy Ordille, Sara Erickson, Deborah R. Ehrlich, H. Paul |
description | The compliance of the bladder which accommodates the holding and voiding of urine is influenced by the amount and type of collagen deposited as well as the packing and organization of collagen fiber bundles. During fetal development, the accumulation of urine within the bladder lumen is associated with the maturation of the bladder's wall. Fetal mouse bladders can undergo maturation as organ cultured explants in defined medium. Polarized light optics of Sirius red-stained sections of fetal mouse bladders in organ culture for 4 days showed that the ligation of both ureters and urethra promoted more orderly packing of collagen fiber bundles within the luminal edge of the lamina propria compared to unligated bladder explants. It is proposed that ligation causes differences in the development and organization of the collagen fiber bundles within the bladder wall. These differences are due to either increases in intravesical pressure, the accumulation of growth factors within the lumen or a combination of both. |
doi_str_mv | 10.1016/S0040-8166(98)80033-5 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70099348</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0040816698800335</els_id><sourcerecordid>70099348</sourcerecordid><originalsourceid>FETCH-LOGICAL-c360t-dd078fafa742341622af966edf2184ffc3bddff38c968c9b37ed6a590a6f67103</originalsourceid><addsrcrecordid>eNqFkEtPGzEQxy1UlIaUjxDJp6o9LIzXu36cqgpRQIrEAXrqwXLWY3C1j9T2RvDtu3koVw6jmdH85_UjZMngigET108AFRSKCfFNq-8KgPOiPiNzVvOy4CDLT2R-knwmFyn9BQBZMTkjM624rqSYkz8PPd2GHAfahhebw9DTwdMxYsaYqO3dPn6NlnaDG1ubMVGP2bZTPiak69Y6h5Hi26a1fU7U4RbbYdNhn7-Qc2_bhJdHvyC_f90-39wXq8e7h5ufq6LhAnLhHEjlrbeyKnnFRFlar4VA50umKu8bvnbOe64aLSZbc4lO2FqDFV5IBnxBvh7mbuLwb8SUTRdSg-10EE5HGgmgNa_UJKwPwiYOKUX0ZhNDZ-O7YWB2UM0eqtkRM1qZPVRTT33L44Jx3aE7dR0pTvUfhzpOX24DRpOagH2DLkRssnFD-GDDf_UxiH0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70099348</pqid></control><display><type>article</type><title>In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Beauboeuf, Andy ; Ordille, Sara ; Erickson, Deborah R. ; Ehrlich, H. Paul</creator><creatorcontrib>Beauboeuf, Andy ; Ordille, Sara ; Erickson, Deborah R. ; Ehrlich, H. Paul</creatorcontrib><description>The compliance of the bladder which accommodates the holding and voiding of urine is influenced by the amount and type of collagen deposited as well as the packing and organization of collagen fiber bundles. During fetal development, the accumulation of urine within the bladder lumen is associated with the maturation of the bladder's wall. Fetal mouse bladders can undergo maturation as organ cultured explants in defined medium. Polarized light optics of Sirius red-stained sections of fetal mouse bladders in organ culture for 4 days showed that the ligation of both ureters and urethra promoted more orderly packing of collagen fiber bundles within the luminal edge of the lamina propria compared to unligated bladder explants. It is proposed that ligation causes differences in the development and organization of the collagen fiber bundles within the bladder wall. These differences are due to either increases in intravesical pressure, the accumulation of growth factors within the lumen or a combination of both.</description><identifier>ISSN: 0040-8166</identifier><identifier>EISSN: 1532-3072</identifier><identifier>DOI: 10.1016/S0040-8166(98)80033-5</identifier><identifier>PMID: 9839476</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Animals ; bladder development ; Collagen ; Collagen - analysis ; Female ; fetal mouse ; Ligation ; Mice ; Mice, Inbred Strains ; organ culture ; Organ Culture Techniques ; Pregnancy ; Ureter - chemistry ; Ureter - cytology ; Urethra - chemistry ; Urethra - cytology ; Urinary Bladder - chemistry ; Urinary Bladder - cytology</subject><ispartof>Tissue & cell, 1998-10, Vol.30 (5), p.531-536</ispartof><rights>1998 Harcourt Brace & Co. Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-dd078fafa742341622af966edf2184ffc3bddff38c968c9b37ed6a590a6f67103</citedby><cites>FETCH-LOGICAL-c360t-dd078fafa742341622af966edf2184ffc3bddff38c968c9b37ed6a590a6f67103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0040-8166(98)80033-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9839476$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Beauboeuf, Andy</creatorcontrib><creatorcontrib>Ordille, Sara</creatorcontrib><creatorcontrib>Erickson, Deborah R.</creatorcontrib><creatorcontrib>Ehrlich, H. Paul</creatorcontrib><title>In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development</title><title>Tissue & cell</title><addtitle>Tissue Cell</addtitle><description>The compliance of the bladder which accommodates the holding and voiding of urine is influenced by the amount and type of collagen deposited as well as the packing and organization of collagen fiber bundles. During fetal development, the accumulation of urine within the bladder lumen is associated with the maturation of the bladder's wall. Fetal mouse bladders can undergo maturation as organ cultured explants in defined medium. Polarized light optics of Sirius red-stained sections of fetal mouse bladders in organ culture for 4 days showed that the ligation of both ureters and urethra promoted more orderly packing of collagen fiber bundles within the luminal edge of the lamina propria compared to unligated bladder explants. It is proposed that ligation causes differences in the development and organization of the collagen fiber bundles within the bladder wall. These differences are due to either increases in intravesical pressure, the accumulation of growth factors within the lumen or a combination of both.</description><subject>Animals</subject><subject>bladder development</subject><subject>Collagen</subject><subject>Collagen - analysis</subject><subject>Female</subject><subject>fetal mouse</subject><subject>Ligation</subject><subject>Mice</subject><subject>Mice, Inbred Strains</subject><subject>organ culture</subject><subject>Organ Culture Techniques</subject><subject>Pregnancy</subject><subject>Ureter - chemistry</subject><subject>Ureter - cytology</subject><subject>Urethra - chemistry</subject><subject>Urethra - cytology</subject><subject>Urinary Bladder - chemistry</subject><subject>Urinary Bladder - cytology</subject><issn>0040-8166</issn><issn>1532-3072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPGzEQxy1UlIaUjxDJp6o9LIzXu36cqgpRQIrEAXrqwXLWY3C1j9T2RvDtu3koVw6jmdH85_UjZMngigET108AFRSKCfFNq-8KgPOiPiNzVvOy4CDLT2R-knwmFyn9BQBZMTkjM624rqSYkz8PPd2GHAfahhebw9DTwdMxYsaYqO3dPn6NlnaDG1ubMVGP2bZTPiak69Y6h5Hi26a1fU7U4RbbYdNhn7-Qc2_bhJdHvyC_f90-39wXq8e7h5ufq6LhAnLhHEjlrbeyKnnFRFlar4VA50umKu8bvnbOe64aLSZbc4lO2FqDFV5IBnxBvh7mbuLwb8SUTRdSg-10EE5HGgmgNa_UJKwPwiYOKUX0ZhNDZ-O7YWB2UM0eqtkRM1qZPVRTT33L44Jx3aE7dR0pTvUfhzpOX24DRpOagH2DLkRssnFD-GDDf_UxiH0</recordid><startdate>19981001</startdate><enddate>19981001</enddate><creator>Beauboeuf, Andy</creator><creator>Ordille, Sara</creator><creator>Erickson, Deborah R.</creator><creator>Ehrlich, H. Paul</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19981001</creationdate><title>In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development</title><author>Beauboeuf, Andy ; Ordille, Sara ; Erickson, Deborah R. ; Ehrlich, H. Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-dd078fafa742341622af966edf2184ffc3bddff38c968c9b37ed6a590a6f67103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>bladder development</topic><topic>Collagen</topic><topic>Collagen - analysis</topic><topic>Female</topic><topic>fetal mouse</topic><topic>Ligation</topic><topic>Mice</topic><topic>Mice, Inbred Strains</topic><topic>organ culture</topic><topic>Organ Culture Techniques</topic><topic>Pregnancy</topic><topic>Ureter - chemistry</topic><topic>Ureter - cytology</topic><topic>Urethra - chemistry</topic><topic>Urethra - cytology</topic><topic>Urinary Bladder - chemistry</topic><topic>Urinary Bladder - cytology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beauboeuf, Andy</creatorcontrib><creatorcontrib>Ordille, Sara</creatorcontrib><creatorcontrib>Erickson, Deborah R.</creatorcontrib><creatorcontrib>Ehrlich, H. Paul</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Tissue & cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beauboeuf, Andy</au><au>Ordille, Sara</au><au>Erickson, Deborah R.</au><au>Ehrlich, H. Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development</atitle><jtitle>Tissue & cell</jtitle><addtitle>Tissue Cell</addtitle><date>1998-10-01</date><risdate>1998</risdate><volume>30</volume><issue>5</issue><spage>531</spage><epage>536</epage><pages>531-536</pages><issn>0040-8166</issn><eissn>1532-3072</eissn><abstract>The compliance of the bladder which accommodates the holding and voiding of urine is influenced by the amount and type of collagen deposited as well as the packing and organization of collagen fiber bundles. During fetal development, the accumulation of urine within the bladder lumen is associated with the maturation of the bladder's wall. Fetal mouse bladders can undergo maturation as organ cultured explants in defined medium. Polarized light optics of Sirius red-stained sections of fetal mouse bladders in organ culture for 4 days showed that the ligation of both ureters and urethra promoted more orderly packing of collagen fiber bundles within the luminal edge of the lamina propria compared to unligated bladder explants. It is proposed that ligation causes differences in the development and organization of the collagen fiber bundles within the bladder wall. These differences are due to either increases in intravesical pressure, the accumulation of growth factors within the lumen or a combination of both.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>9839476</pmid><doi>10.1016/S0040-8166(98)80033-5</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0040-8166 |
ispartof | Tissue & cell, 1998-10, Vol.30 (5), p.531-536 |
issn | 0040-8166 1532-3072 |
language | eng |
recordid | cdi_proquest_miscellaneous_70099348 |
source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Animals bladder development Collagen Collagen - analysis Female fetal mouse Ligation Mice Mice, Inbred Strains organ culture Organ Culture Techniques Pregnancy Ureter - chemistry Ureter - cytology Urethra - chemistry Urethra - cytology Urinary Bladder - chemistry Urinary Bladder - cytology |
title | In vitro ligation of ureters and urethra modulates fetal mouse bladder explants development |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T07%3A49%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20vitro%20ligation%20of%20ureters%20and%20urethra%20modulates%20fetal%20mouse%20bladder%20explants%20development&rft.jtitle=Tissue%20&%20cell&rft.au=Beauboeuf,%20Andy&rft.date=1998-10-01&rft.volume=30&rft.issue=5&rft.spage=531&rft.epage=536&rft.pages=531-536&rft.issn=0040-8166&rft.eissn=1532-3072&rft_id=info:doi/10.1016/S0040-8166(98)80033-5&rft_dat=%3Cproquest_cross%3E70099348%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70099348&rft_id=info:pmid/9839476&rft_els_id=S0040816698800335&rfr_iscdi=true |