Transport properties of bovine and reindeer β-lactoglobulin in the Caco-2 cell model

β-Lactoglobulin (βLG) is a protein that binds ligands like fatty acids and retinol into the hydrophobic pocket. Our purpose was to study bovine and reindeer βLG as transporter molecules and compare their transport properties across Caco-2 cell membrane. The reindeer βLG has more valuable binder char...

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Veröffentlicht in:	International journal of pharmaceutics 2008-01, Vol.347 (1), p.1-8
Hauptverfasser:	Riihimäki, Laura, Galkin, Anna, Finel, Moshe, Heikura, Jonna, Valkonen, Kaija, Virtanen, Vesa, Laaksonen, Reijo, Slotte, J. Peter, Vuorela, Pia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Transport Caco-2 Cells Caco-2 monolayer Carrier Proteins - metabolism Cattle Cell Membrane - metabolism Cholesterol - metabolism Electric Impedance General pharmacology Humans Lactoglobulins - metabolism Lactoglobulins - pharmacokinetics Ligand Ligands Medical sciences Palmitic Acid - metabolism Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Reindeer Transport Vitamin A - metabolism β-Lactoglobulin
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