A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13- 15, a region subject to LOH and rearrangement in human carcinoma cell lines

The ETS transcription factors are a large family implicated in the control of cellular proliferation and tumorigenesis. In addition, chromosomal translocations involving ETS family members are associated with a range of different human cancers. Given the extensive involvement of ETS factors in tumor...

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Veröffentlicht in:	Oncogene 1998-11, Vol.17 (21), p.2719-2732
Hauptverfasser:	JIONG ZHOU, NG, A. Y. N, TYMMS, M. J, JERMIIN, L. S, SETH, A. K, THOMAS, R. S, KOLA, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological and medical sciences Breast Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Carcinoma - genetics Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Chromosome 11 Chromosome Mapping Chromosome translocations Chromosomes, Human, Pair 11 - genetics COS Cells DNA, Complementary - genetics ELF protein Epithelium ETS protein Female Fundamental and applied biological sciences. Psychology Gene Expression Gene Library Gene mapping Gene rearrangement Genes Heterozygosity Humans Kidney Neoplasms - genetics Kidney Neoplasms - pathology Kidneys Loss of Heterozygosity Lung - chemistry Male Mammary gland Mice - genetics Molecular and cellular biology Molecular Sequence Data Multigene Family Nucleotide sequence Organ Specificity Phylogeny Prostate Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Proto-Oncogene Proteins c-ets Regulatory Sequences, Nucleic Acid Sequence Alignment Sequence Homology, Amino Acid Transcription factors Transcription Factors - analysis Transcription Factors - genetics Transcription Factors - isolation & purification Transcription Factors - physiology Transcription, Genetic Transfection Tumor cell lines Tumor Cells, Cultured Tumorigenesis
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