Organization, structure and evolution of 41kb of genomic DNA spanning the D-J-C region of the sheep TRB locus

A genomic region of 41,045bp encompassing the 3′-end of the sheep T cell receptor beta chain was sequenced. Extensive molecular analysis has revealed that this region retains a unique structural feature for the presence of a third D-J-C cluster, never detected in any other mammalian species examined...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular immunology 2008-01, Vol.45 (2), p.493-509
Hauptverfasser:	Antonacci, R., Di Tommaso, S., Lanave, C., Cribiu, E.P., Ciccarese, S., Massari, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Pairing Base Sequence Chromosomes, Artificial, Bacterial Clone Cells D-J-C-region DNA - chemistry DNA - genetics Evolution, Molecular Exons - genetics Genes, T-Cell Receptor beta Genes, T-Cell Receptor delta Genome - genetics Humans Introns - genetics Molecular Sequence Data Phylogeny Receptors, Antigen, T-Cell, alpha-beta - chemistry Receptors, Antigen, T-Cell, alpha-beta - genetics Sequence Alignment Sheep Sheep - genetics T-cell receptor Transcription, Genetic TRB locus β-Chain
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!