Tracheal intubation without neuromuscular blockade in children: a comparison of propofol combined either with alfentanil or remifentanil
Forty healthy children, aged between two and 12 years of age undergoing elective surgery where the anaesthetic technique involved tracheal intubation followed by spontaneous ventilation were studied. Induction of anaesthesia was with either alfentanil 15 μg·kg−1 or remifentanil 1 μg·kg−1 followed by...
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| Veröffentlicht in: | Pediatric anesthesia 1998-11, Vol.8 (6), p.467-471 |
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| creator | Robinson O'Brien Kumar, R Morton |
| description | Forty healthy children, aged between two and 12 years of age undergoing elective surgery where the anaesthetic technique involved tracheal intubation followed by spontaneous ventilation were studied. Induction of anaesthesia was with either alfentanil 15 μg·kg−1 or remifentanil 1 μg·kg−1 followed by propofol 4 mg·kg−1 to which lignocaine 0.2 mg·kg−1 had been added. Intubating conditions were graded on a four point scale for ease of laryngoscopy, vocal cord position, degree of coughing, jaw relaxation and limb movement. All children were successfully intubated at the first attempt. There were no significant differences in the assessments of intubating conditions between the two groups. Arterial blood pressure and heart changes were similar in the two groups with both alfentanil and remifentanil attenuating the haemodynamic response to tracheal intubation. The time taken to resumption of spontaneous ventilation was similar in both groups. |
| doi_str_mv | 10.1046/j.1460-9592.1998.00275.x |
| format | Article |
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Induction of anaesthesia was with either alfentanil 15 μg·kg−1 or remifentanil 1 μg·kg−1 followed by propofol 4 mg·kg−1 to which lignocaine 0.2 mg·kg−1 had been added. Intubating conditions were graded on a four point scale for ease of laryngoscopy, vocal cord position, degree of coughing, jaw relaxation and limb movement. All children were successfully intubated at the first attempt. There were no significant differences in the assessments of intubating conditions between the two groups. Arterial blood pressure and heart changes were similar in the two groups with both alfentanil and remifentanil attenuating the haemodynamic response to tracheal intubation. The time taken to resumption of spontaneous ventilation was similar in both groups.</description><identifier>ISSN: 1155-5645</identifier><identifier>EISSN: 1460-9592</identifier><identifier>DOI: 10.1046/j.1460-9592.1998.00275.x</identifier><identifier>PMID: 9836210</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>alfentanil ; Alfentanil - pharmacology ; anaesthetics ; Analgesics ; Anesthetics, Intravenous - pharmacology ; Biological and medical sciences ; Child ; Child, Preschool ; Female ; Hemodynamics - drug effects ; Humans ; intravenous ; intubation ; Intubation, Intratracheal ; Lidocaine ; Male ; Medical sciences ; Neuropharmacology ; opioid ; Pharmacology. Drug treatments ; Piperidines - pharmacology ; Propofol ; remifentanil ; tracheal</subject><ispartof>Pediatric anesthesia, 1998-11, Vol.8 (6), p.467-471</ispartof><rights>1998 Blackwell Science Ltd.</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4305-7d03ff9c58c8a0aa712249bb94688c8df19ae01fea589a350d175d5ce94b5e243</citedby><cites>FETCH-LOGICAL-c4305-7d03ff9c58c8a0aa712249bb94688c8df19ae01fea589a350d175d5ce94b5e243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1460-9592.1998.00275.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1460-9592.1998.00275.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27911,27912,45561,45562</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1590653$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9836210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Robinson</creatorcontrib><creatorcontrib>O'Brien</creatorcontrib><creatorcontrib>Kumar, R</creatorcontrib><creatorcontrib>Morton</creatorcontrib><title>Tracheal intubation without neuromuscular blockade in children: a comparison of propofol combined either with alfentanil or remifentanil</title><title>Pediatric anesthesia</title><addtitle>Paediatr Anaesth</addtitle><description>Forty healthy children, aged between two and 12 years of age undergoing elective surgery where the anaesthetic technique involved tracheal intubation followed by spontaneous ventilation were studied. Induction of anaesthesia was with either alfentanil 15 μg·kg−1 or remifentanil 1 μg·kg−1 followed by propofol 4 mg·kg−1 to which lignocaine 0.2 mg·kg−1 had been added. Intubating conditions were graded on a four point scale for ease of laryngoscopy, vocal cord position, degree of coughing, jaw relaxation and limb movement. All children were successfully intubated at the first attempt. There were no significant differences in the assessments of intubating conditions between the two groups. Arterial blood pressure and heart changes were similar in the two groups with both alfentanil and remifentanil attenuating the haemodynamic response to tracheal intubation. The time taken to resumption of spontaneous ventilation was similar in both groups.</description><subject>alfentanil</subject><subject>Alfentanil - pharmacology</subject><subject>anaesthetics</subject><subject>Analgesics</subject><subject>Anesthetics, Intravenous - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hemodynamics - drug effects</subject><subject>Humans</subject><subject>intravenous</subject><subject>intubation</subject><subject>Intubation, Intratracheal</subject><subject>Lidocaine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>opioid</subject><subject>Pharmacology. Drug treatments</subject><subject>Piperidines - pharmacology</subject><subject>Propofol</subject><subject>remifentanil</subject><subject>tracheal</subject><issn>1155-5645</issn><issn>1460-9592</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUc1u1DAQjhColMIjIPmAuCXYSZzEiEtV0QWpFFSKOFoTZ6z11rEXO1G3b8Bj43SX5crJ4_l-ZvRNlhFGC0br5t2mYHVDc8FFWTAhuoLSsuXF7kl2egSepppxnvOm5s-zFzFuKGVV2ZQn2YnoqqZk9DT7fRtArREsMW6ae5iMd-TeTGs_T8ThHPw4RzVbCKS3Xt3BgIlJ1NrYIaB7T4AoP24hmJiEXpNt8FuvvV3avXE4EExuGB5NCViNbgJnLPGBBBzN3__L7JkGG_HV4T3Lflx-vL34lF99XX2-OL_KVV1RnrcDrbQWineqAwrQsrKsRd-LuulSa9BMAFKmEXgnoOJ0YC0fuEJR9xzLujrL3u5906K_ZoyTHE1UaC049HOULaVdy2ibiN2eqIKPMaCW22BGCA-SUbkcQW7kkrVcspbLEeTjEeQuSV8fZsz9iMNReEg94W8OOESVIgnglIn__LmgDa8S7cOedm8sPvz3ePnt_DoVSZ7v5SZOuDvKIdzJpq0S8-f1Sl6uxBfOv9_Im-oPQWO07A</recordid><startdate>199811</startdate><enddate>199811</enddate><creator>Robinson</creator><creator>O'Brien</creator><creator>Kumar, R</creator><creator>Morton</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199811</creationdate><title>Tracheal intubation without neuromuscular blockade in children: a comparison of propofol combined either with alfentanil or remifentanil</title><author>Robinson ; O'Brien ; Kumar, R ; Morton</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4305-7d03ff9c58c8a0aa712249bb94688c8df19ae01fea589a350d175d5ce94b5e243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>alfentanil</topic><topic>Alfentanil - pharmacology</topic><topic>anaesthetics</topic><topic>Analgesics</topic><topic>Anesthetics, Intravenous - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Hemodynamics - drug effects</topic><topic>Humans</topic><topic>intravenous</topic><topic>intubation</topic><topic>Intubation, Intratracheal</topic><topic>Lidocaine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>opioid</topic><topic>Pharmacology. Drug treatments</topic><topic>Piperidines - pharmacology</topic><topic>Propofol</topic><topic>remifentanil</topic><topic>tracheal</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robinson</creatorcontrib><creatorcontrib>O'Brien</creatorcontrib><creatorcontrib>Kumar, R</creatorcontrib><creatorcontrib>Morton</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robinson</au><au>O'Brien</au><au>Kumar, R</au><au>Morton</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tracheal intubation without neuromuscular blockade in children: a comparison of propofol combined either with alfentanil or remifentanil</atitle><jtitle>Pediatric anesthesia</jtitle><addtitle>Paediatr Anaesth</addtitle><date>1998-11</date><risdate>1998</risdate><volume>8</volume><issue>6</issue><spage>467</spage><epage>471</epage><pages>467-471</pages><issn>1155-5645</issn><eissn>1460-9592</eissn><abstract>Forty healthy children, aged between two and 12 years of age undergoing elective surgery where the anaesthetic technique involved tracheal intubation followed by spontaneous ventilation were studied. Induction of anaesthesia was with either alfentanil 15 μg·kg−1 or remifentanil 1 μg·kg−1 followed by propofol 4 mg·kg−1 to which lignocaine 0.2 mg·kg−1 had been added. Intubating conditions were graded on a four point scale for ease of laryngoscopy, vocal cord position, degree of coughing, jaw relaxation and limb movement. All children were successfully intubated at the first attempt. There were no significant differences in the assessments of intubating conditions between the two groups. Arterial blood pressure and heart changes were similar in the two groups with both alfentanil and remifentanil attenuating the haemodynamic response to tracheal intubation. The time taken to resumption of spontaneous ventilation was similar in both groups.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>9836210</pmid><doi>10.1046/j.1460-9592.1998.00275.x</doi><tpages>5</tpages></addata></record> |
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| ispartof | Pediatric anesthesia, 1998-11, Vol.8 (6), p.467-471 |
| issn | 1155-5645 1460-9592 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | alfentanil Alfentanil - pharmacology anaesthetics Analgesics Anesthetics, Intravenous - pharmacology Biological and medical sciences Child Child, Preschool Female Hemodynamics - drug effects Humans intravenous intubation Intubation, Intratracheal Lidocaine Male Medical sciences Neuropharmacology opioid Pharmacology. Drug treatments Piperidines - pharmacology Propofol remifentanil tracheal |
| title | Tracheal intubation without neuromuscular blockade in children: a comparison of propofol combined either with alfentanil or remifentanil |
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