Induction of Immunologic Memory by Conjugated vs Plain Meningococcal C Polysaccharide Vaccine in Toddlers: A Randomized Controlled Trial

CONTEXT.— Meningococcal polysaccharide vaccines are not used routinely in infants and toddlers, the groups at highest risk of invasive disease, because of poor immunologic responses to the Neisseria meningitidis serogroup C polysaccharide in these age groups. Meningococcal C conjugate vaccines offer...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 1998-11, Vol.280 (19), p.1685-1689
Hauptverfasser:	MacDonald, Noni E, Halperin, Scott A, Law, Barbara J, Forrest, Bruce, Danzig, Lisa E, Granoff, Dan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Bacterial - biosynthesis Antibodies, Bacterial - immunology Bacterial Vaccines - administration & dosage Bacterial Vaccines - immunology Biological and medical sciences Children & youth Enzyme-Linked Immunosorbent Assay Epidemiology. Vaccinations General aspects Hepatitis B Vaccines - immunology Humans Immunization, Secondary Immunoglobulin G - analysis Immunoglobulin G - immunology Immunologic Memory Immunology Infant Infectious diseases Medical research Medical sciences Meningitis Meningococcal Infections - prevention & control Neisseria meningitidis Neisseria meningitidis - classification Neisseria meningitidis - immunology Polysaccharides, Bacterial - immunology Serotyping Vaccination Vaccines Vaccines, Conjugate - administration & dosage Vaccines, Conjugate - immunology
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