Phospholipid Interaction Induces Molecular-level Polymorphism in Apolipoprotein C-II Amyloid Fibrils via Alternative Assembly Pathways

A common feature of many of the most important and prominent amyloid-forming proteins is their ability to bind lipids and lipid complexes. Lipids are ubiquitous components of disease-associated amyloid plaques and deposits in humans, yet the specific roles of lipid in the process of amyloid fibril f...

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Veröffentlicht in:Journal of molecular biology 2008-01, Vol.375 (1), p.240-256
Hauptverfasser: Griffin, Michael D.W., Mok, Melva L.Y., Wilson, Leanne M., Pham, Chi L.L., Waddington, Lynne J., Perugini, Matthew A., Howlett, Geoffrey J.
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Sprache:eng
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