Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance

To elucidate the possible involvement of gankyrin in ESCC progression and the effect of its down‐regulation in ESCC, we investigated the expression of gankyrin in ESCC tissues comparing it with the corresponding normal esophageal epithelia and tested a short‐hairpin RNA (shRNA) expression vector for...

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Veröffentlicht in:	International journal of cancer 2008-01, Vol.122 (2), p.325-332
Hauptverfasser:	Ortiz, Cristian M., Ito, Tetsuo, Tanaka, Eiji, Tsunoda, Shigeru, Nagayama, Satoshi, Sakai, Yoshiharu, Higashitsuji, Hiroaki, Fujita, Jun, Shimada, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Biological and medical sciences Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - metabolism cell cycle Cell Line, Tumor Cell Proliferation clinical significance esophageal cancer Esophageal Neoplasms - diagnosis Esophageal Neoplasms - metabolism Esophagus Female gankyrin Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Regulation, Neoplastic HeLa Cells Humans Male Medical sciences Mice Mice, Nude Middle Aged Neoplasm Transplantation novel oncogene Proteasome Endopeptidase Complex - biosynthesis Proteasome Endopeptidase Complex - physiology Proto-Oncogene Proteins - biosynthesis Proto-Oncogene Proteins - physiology Transcription Factors - biosynthesis Transcription Factors - physiology Tumors
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