A 2-week pretreatment with 13-cis-retinoic acid + interferon-alpha-2a prior to definitive radiation improves tumor tissue oxygenation in cervical cancers

We have evaluated the tumor tissue pO2 in cervical cancers in patients treated with 13-cis-retinoic acid and interferon-alpha-2a prior to and during radiotherapy. From June 1995 through April 1997, 22 patients with squamous cell carcinoma FIGO IIB/III of the cervix who were scheduled for definitive...

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Veröffentlicht in:	Strahlentherapie und Onkologie 1998-11, Vol.174 (11), p.571-574
Hauptverfasser:	Dunst, J, Hänsgen, G, Krause, U, Füchsel, G, Köhler, U, Becker, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Agents - administration & dosage Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - radiotherapy Cell Hypoxia Female Humans Interferon-alpha - administration & dosage Isotretinoin - administration & dosage Keratolytic Agents - administration & dosage Middle Aged Oxygen - metabolism Radiotherapy Dosage Recombinant Proteins Time Factors Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - radiotherapy
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