Increased baseline levels of platelet P-selectin, and platelet-endothelial cell adhesion molecule-1 in patients with acute myocardial infarction as predictors of unsuccessful thrombolysis

BACKGROUNDPlatelets play a pivotal role in the pathogenesis of acute myocardial infarction and their activation can cause thrombolysis to fail. METHODSBaseline aggregation of platelets and expression of major surface receptors measured by flow cytometry were compared with clinical outcome after thro...

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Veröffentlicht in:	Coronary artery disease 1998, Vol.9 (7), p.451-456
Hauptverfasser:	Gurbel, Paul A, Serebruany, Victor L, Shustov, Andrew R, Dalesandro, Margaret, Gumbs, Cindy I, Grablutz, Laura B, Bahr, Raymond D, Ohman, E Magnus, Topol, Eric J
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Platelets - metabolism Female Fibrinolytic Agents - therapeutic use Flow Cytometry Humans Male Middle Aged Myocardial Infarction - blood Myocardial Infarction - drug therapy P-Selectin - blood Plasminogen Activators - therapeutic use Platelet Aggregation Platelet Endothelial Cell Adhesion Molecule-1 - blood Recombinant Proteins - therapeutic use Thrombolytic Therapy Time Factors Tissue Plasminogen Activator - therapeutic use Treatment Failure
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