Pseudotumour cerebri after varicella
Thrombotic complications in children with varicella are well known. Transient protein S deficiency due to the presence of an anti-protein S antibody seems to be responsible at least in part. In an 8-year-old girl, pseudotumour cerebri with abducens palsy and ileofemoral vein thrombosis occurred 3 we...
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Veröffentlicht in: | European journal of pediatrics 1998-11, Vol.157 (11), p.904-906 |
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container_title | European journal of pediatrics |
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creator | KONRAD, D KUSTER, H HUNZIKER, U. A |
description | Thrombotic complications in children with varicella are well known. Transient protein S deficiency due to the presence of an anti-protein S antibody seems to be responsible at least in part. In an 8-year-old girl, pseudotumour cerebri with abducens palsy and ileofemoral vein thrombosis occurred 3 weeks after chickenpox. A transient elevation of anti-protein S auto-antibodies was identified. Under treatment with heparin the pseudotumour cerebri rapidly disappeared but the iliofemoral thrombosis persisted.
Thrombotic complications after varicella might be mediated at least in part by antibodies against protein S. Early recognition of this condition permits appropriate treatment with recombinant tissue-type plasminogen activator. |
doi_str_mv | 10.1007/s004310050964 |
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Thrombotic complications after varicella might be mediated at least in part by antibodies against protein S. Early recognition of this condition permits appropriate treatment with recombinant tissue-type plasminogen activator.</description><subject>Biological and medical sciences</subject><subject>Chickenpox - complications</subject><subject>Child</subject><subject>Female</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Protein S Deficiency - complications</subject><subject>Pseudotumor Cerebri - blood</subject><subject>Pseudotumor Cerebri - etiology</subject><subject>Venous Thrombosis - etiology</subject><subject>Viral diseases</subject><subject>Viral diseases of the nervous system</subject><issn>0340-6199</issn><issn>1432-1076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkM9LxDAQhYMo67p69CgssnirTjJp0hxl8Rcs6EHPIU2n0KXdrkkr-N_bdYuipxl4H4-Px9g5h2sOoG8igMThS8EoecCmXKJIOGh1yKaAEhLFjTlmJzGuYeANzyZsYjJMJcopW7xE6ou265u2D3NPgfJQzV3ZUZh_uFB5qmt3yo5KV0c6G--Mvd3fvS4fk9Xzw9PydpV4lLJLZOELkWcFcqFAZBmBLFCmqcyQjPGkuQBFHIQm5Dr3pBxikaImMqUngTN2te_dhva9p9jZporfBhtq-2j14K94tgMv_4HrQX8zuFkhuFFamx2U7CEf2hgDlXYbqsaFT8vB7qazf6Yb-IuxtM8bKn7ocashX4y5i97VZXAbX8Xf0tQYIyV-ATelcuk</recordid><startdate>19981101</startdate><enddate>19981101</enddate><creator>KONRAD, D</creator><creator>KUSTER, H</creator><creator>HUNZIKER, U. 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A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pseudotumour cerebri after varicella</atitle><jtitle>European journal of pediatrics</jtitle><addtitle>Eur J Pediatr</addtitle><date>1998-11-01</date><risdate>1998</risdate><volume>157</volume><issue>11</issue><spage>904</spage><epage>906</epage><pages>904-906</pages><issn>0340-6199</issn><eissn>1432-1076</eissn><coden>EJPEDT</coden><abstract>Thrombotic complications in children with varicella are well known. Transient protein S deficiency due to the presence of an anti-protein S antibody seems to be responsible at least in part. In an 8-year-old girl, pseudotumour cerebri with abducens palsy and ileofemoral vein thrombosis occurred 3 weeks after chickenpox. A transient elevation of anti-protein S auto-antibodies was identified. Under treatment with heparin the pseudotumour cerebri rapidly disappeared but the iliofemoral thrombosis persisted.
Thrombotic complications after varicella might be mediated at least in part by antibodies against protein S. Early recognition of this condition permits appropriate treatment with recombinant tissue-type plasminogen activator.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>9835434</pmid><doi>10.1007/s004310050964</doi><tpages>3</tpages></addata></record> |
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language | eng |
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source | MEDLINE; SpringerNature Journals |
subjects | Biological and medical sciences Chickenpox - complications Child Female Human viral diseases Humans Infectious diseases Medical sciences Protein S Deficiency - complications Pseudotumor Cerebri - blood Pseudotumor Cerebri - etiology Venous Thrombosis - etiology Viral diseases Viral diseases of the nervous system |
title | Pseudotumour cerebri after varicella |
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