Zebrafish contains two Pax6 genes involved in eye development

The Pax6 genes of both vertebrates and invertebrates are expressed in the developing eye and in the central nervous system. These genes encode transcription factors with two DNA-binding domains, an N-terminal paired domain and a homeodomain separated by a flexible linker region. Ectopic eye structur...

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Veröffentlicht in:	Mechanisms of development 1998-10, Vol.77 (2), p.185-196
Hauptverfasser:	Nornes, Svanhild, Clarkson, Michael, Mikkola, Ingvild, Pedersen, Marit, Bardsley, Anne, Martinez, Juan Pedro, Krauss, Stefan, Johansen, Terje
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Animals, Genetically Modified Base Sequence Cloning, Molecular DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drosophila - genetics Embryo, Nonmammalian Eye - embryology Eye - growth & development Eye Abnormalities - embryology Eye Abnormalities - genetics Eye development Eye Proteins - genetics Eye Proteins - metabolism Gene duplication Gene Expression Regulation, Developmental Homeodomain Proteins Humans Mice Molecular Sequence Data Paired Box Transcription Factors Pax6 PAX6 Transcription Factor Repressor Proteins Trans-Activators - genetics Trans-Activators - metabolism Zebrafish Zebrafish - embryology Zebrafish - genetics
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