Controlled randomized clinical trials

It is generally agreed that the first comparative clinical trial in history was done by James Lind in 1747, in the treatment of scurvy. The general bases of modern experimental medicine were published by Claude Bernard in 1865. However, it is the development of new drugs and the evolution of methodo...

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Veröffentlicht in:Bulletin de l'Académie nationale de médecine 2007-04, Vol.191 (4-5), p.739-56; discussion 756-8
1. Verfasser: Jaillon, Patrice
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Sprache:fre
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