Imaging Findings in a 3-year-old Girl with Type III Pleuropulmonary Blastoma
Pleuropulmonary blastoma (PPB) is a rare dysembryonic intrathoracic neoplasm in children. It is a malignant tumour originating from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was diagnosed as having a type III PPB according to his...
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Veröffentlicht in: | In vivo (Athens) 2007-11, Vol.21 (6), p.1119-1122 |
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creator | Geiger, J Walter, K Uhl, M Bley, T A Jüttner, E Brink, I Kirschbaum, A Kontny, U |
description | Pleuropulmonary blastoma (PPB) is a rare dysembryonic intrathoracic neoplasm in children. It is a malignant tumour originating
from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was
diagnosed as having a type III PPB according to histological results attained by open biopsy. Imaging by CT and MRI revealed
the exact size of the tumour involving the left lower lobe with displacement of the mediastinum and the diaphragm. Additional
FDG-PET was important to evaluate tumour vitality and to decide the time of surgery, which was performed after 12 weeks of
chemotherapy with the CWS2002P protocol. After R0 resection without complications and postoperative chemotherapy, the child
continues to be in complete remission. This case underlines the importance of radical surgery of the aggressive neoplasm in
combination with chemotherapy and the usefulness of multimodal imaging for the optimal planning of local therapy. |
format | Article |
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from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was
diagnosed as having a type III PPB according to histological results attained by open biopsy. Imaging by CT and MRI revealed
the exact size of the tumour involving the left lower lobe with displacement of the mediastinum and the diaphragm. Additional
FDG-PET was important to evaluate tumour vitality and to decide the time of surgery, which was performed after 12 weeks of
chemotherapy with the CWS2002P protocol. After R0 resection without complications and postoperative chemotherapy, the child
continues to be in complete remission. This case underlines the importance of radical surgery of the aggressive neoplasm in
combination with chemotherapy and the usefulness of multimodal imaging for the optimal planning of local therapy.</description><identifier>ISSN: 0258-851X</identifier><identifier>EISSN: 1791-7549</identifier><identifier>PMID: 18210767</identifier><language>eng</language><publisher>Greece: International Institute of Anticancer Research</publisher><subject>Child, Preschool ; Female ; Humans ; Lung Neoplasms - diagnosis ; Lung Neoplasms - diagnostic imaging ; Magnetic Resonance Imaging ; Pleural Neoplasms - diagnosis ; Pleural Neoplasms - diagnostic imaging ; Positron-Emission Tomography ; Tomography, X-Ray Computed</subject><ispartof>In vivo (Athens), 2007-11, Vol.21 (6), p.1119-1122</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18210767$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Geiger, J</creatorcontrib><creatorcontrib>Walter, K</creatorcontrib><creatorcontrib>Uhl, M</creatorcontrib><creatorcontrib>Bley, T A</creatorcontrib><creatorcontrib>Jüttner, E</creatorcontrib><creatorcontrib>Brink, I</creatorcontrib><creatorcontrib>Kirschbaum, A</creatorcontrib><creatorcontrib>Kontny, U</creatorcontrib><title>Imaging Findings in a 3-year-old Girl with Type III Pleuropulmonary Blastoma</title><title>In vivo (Athens)</title><addtitle>In Vivo</addtitle><description>Pleuropulmonary blastoma (PPB) is a rare dysembryonic intrathoracic neoplasm in children. It is a malignant tumour originating
from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was
diagnosed as having a type III PPB according to histological results attained by open biopsy. Imaging by CT and MRI revealed
the exact size of the tumour involving the left lower lobe with displacement of the mediastinum and the diaphragm. Additional
FDG-PET was important to evaluate tumour vitality and to decide the time of surgery, which was performed after 12 weeks of
chemotherapy with the CWS2002P protocol. After R0 resection without complications and postoperative chemotherapy, the child
continues to be in complete remission. This case underlines the importance of radical surgery of the aggressive neoplasm in
combination with chemotherapy and the usefulness of multimodal imaging for the optimal planning of local therapy.</description><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Lung Neoplasms - diagnostic imaging</subject><subject>Magnetic Resonance Imaging</subject><subject>Pleural Neoplasms - diagnosis</subject><subject>Pleural Neoplasms - diagnostic imaging</subject><subject>Positron-Emission Tomography</subject><subject>Tomography, X-Ray Computed</subject><issn>0258-851X</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z8tKAzEYBeAgiq3VV5BsdBfIpZOZLLVYHSjoooK78HeSdCKZi8mMpW_vQOvqbD4O51ygOcsVI3m2VJdoTnlWkCJjXzN0k9I3pTKnlF-jGSs4o7nM52hTNrD37R6vfWumTNi3GLAgRwuRdMHgVx8DPvihxttjb3FZlvgj2DF2_RiaroV4xM8B0tA1cIuuHIRk7865QJ_rl-3qjWzeX8vV04bUXKiBuCLLKqoy48BwISivClkZYw0wyanZObF0IJVwyoh852wljYClqrgA4AqkWKDHU28fu5_RpkE3PlU2BGhtNyY9vcwFFWyC92c47hprdB99Mw3W__8n8HACtd_XBx-tTg2EMHGh_S9nWmrGmBJ_lY1kcQ</recordid><startdate>20071101</startdate><enddate>20071101</enddate><creator>Geiger, J</creator><creator>Walter, K</creator><creator>Uhl, M</creator><creator>Bley, T A</creator><creator>Jüttner, E</creator><creator>Brink, I</creator><creator>Kirschbaum, A</creator><creator>Kontny, U</creator><general>International Institute of Anticancer Research</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20071101</creationdate><title>Imaging Findings in a 3-year-old Girl with Type III Pleuropulmonary Blastoma</title><author>Geiger, J ; Walter, K ; Uhl, M ; Bley, T A ; Jüttner, E ; Brink, I ; Kirschbaum, A ; Kontny, U</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h239t-f855c095dfad23302c86cddeda1620dbf34fa693f9d37bfec6d3a49c23aa29a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Lung Neoplasms - diagnosis</topic><topic>Lung Neoplasms - diagnostic imaging</topic><topic>Magnetic Resonance Imaging</topic><topic>Pleural Neoplasms - diagnosis</topic><topic>Pleural Neoplasms - diagnostic imaging</topic><topic>Positron-Emission Tomography</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Geiger, J</creatorcontrib><creatorcontrib>Walter, K</creatorcontrib><creatorcontrib>Uhl, M</creatorcontrib><creatorcontrib>Bley, T A</creatorcontrib><creatorcontrib>Jüttner, E</creatorcontrib><creatorcontrib>Brink, I</creatorcontrib><creatorcontrib>Kirschbaum, A</creatorcontrib><creatorcontrib>Kontny, U</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Geiger, J</au><au>Walter, K</au><au>Uhl, M</au><au>Bley, T A</au><au>Jüttner, E</au><au>Brink, I</au><au>Kirschbaum, A</au><au>Kontny, U</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Imaging Findings in a 3-year-old Girl with Type III Pleuropulmonary Blastoma</atitle><jtitle>In vivo (Athens)</jtitle><addtitle>In Vivo</addtitle><date>2007-11-01</date><risdate>2007</risdate><volume>21</volume><issue>6</issue><spage>1119</spage><epage>1122</epage><pages>1119-1122</pages><issn>0258-851X</issn><eissn>1791-7549</eissn><abstract>Pleuropulmonary blastoma (PPB) is a rare dysembryonic intrathoracic neoplasm in children. It is a malignant tumour originating
from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was
diagnosed as having a type III PPB according to histological results attained by open biopsy. Imaging by CT and MRI revealed
the exact size of the tumour involving the left lower lobe with displacement of the mediastinum and the diaphragm. Additional
FDG-PET was important to evaluate tumour vitality and to decide the time of surgery, which was performed after 12 weeks of
chemotherapy with the CWS2002P protocol. After R0 resection without complications and postoperative chemotherapy, the child
continues to be in complete remission. This case underlines the importance of radical surgery of the aggressive neoplasm in
combination with chemotherapy and the usefulness of multimodal imaging for the optimal planning of local therapy.</abstract><cop>Greece</cop><pub>International Institute of Anticancer Research</pub><pmid>18210767</pmid><tpages>4</tpages></addata></record> |
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subjects | Child, Preschool Female Humans Lung Neoplasms - diagnosis Lung Neoplasms - diagnostic imaging Magnetic Resonance Imaging Pleural Neoplasms - diagnosis Pleural Neoplasms - diagnostic imaging Positron-Emission Tomography Tomography, X-Ray Computed |
title | Imaging Findings in a 3-year-old Girl with Type III Pleuropulmonary Blastoma |
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