Independent coupling of the human tachykinin NK2 receptor to phospholipases C and A2 in transfected Chinese hamster ovary cells

The human tachykinin NK2 receptor stably expressed in Chinese hamster ovary cells (CHO-hNK2R cells) was characterized by studying the effect of neurokinin A (NKA), the preferred natural ligand, and that of other agonists and antagonists in both binding experiments and functional assays. Competition...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 1998-10, Vol.358 (4), p.395-403
Hauptverfasser:	Catalioto, R M, Cucchi, P, Renzetti, A R, Criscuoli, M, Maggi, C A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid - metabolism Binding Sites Calcium - metabolism Calcium Channel Blockers - pharmacology CHO Cells Cricetinae Dinoprostone - metabolism Humans Inositol 1,4,5-Trisphosphate - biosynthesis Pertussis Toxin Phospholipases A - physiology Phospholipases A2 Receptors, Neurokinin-2 - physiology Transfection Type C Phospholipases - physiology Virulence Factors, Bordetella - pharmacology
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