Control of lymphocyte function through CD27–CD70 interactions

In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors, whereas for the induction of CD70 expression additional (co–...

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Veröffentlicht in:	Seminars in immunology 1998-12, Vol.10 (6), p.491-499
Hauptverfasser:	Lens, Susanne M.A., Tesselaar, Kiki, van Oers, Marinus H.J., van Lier, René A.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD B-Lymphocytes - immunology CD27 Ligand CD27, CD70, lymphocytes, TNFR–family Cell Differentiation Gene Expression Regulation Gene Expression Regulation, Neoplastic Humans Lymphocyte Activation Lymphoma, B-Cell Membrane Proteins - immunology Membrane Proteins - metabolism Signal Transduction T-Lymphocytes - immunology Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism
Online-Zugang:	Volltext
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