Bcl-2 and p53 overexpression as associated risk factors in transitional cell carcinoma of the bladder

Bcl-2 and p53 genes are implicated in cell cycle regulation with roles on programmed cell death. Consequently, presence of Bcl-2 and nuclear accumulation of p53 were proposed to confer a growth advantage tumour cells. We have investigated their role as prognostic factors in fresh tumour samples from...

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Veröffentlicht in:	International urology and nephrology 1998, Vol.30 (4), p.455-461
Hauptverfasser:	Atuğ, F, Türkeri, L, Ozyürek, M, Akdaş, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - pathology Humans Immunohistochemistry Neoplasm Recurrence, Local - diagnosis Prognosis Proto-Oncogene Proteins c-bcl-2 - metabolism Tumor Suppressor Protein p53 - metabolism Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
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