Lithium induced changes in intracellular free magnesium concentration in isolated rat ventricular myocytes

We have examined the effect of exposing isolated rat ventricular myocytes to lithium while measuring cytosolic free magnesium ([Mg2+]i) and calcium ([Ca2+]i) levels with the fluorescent, ion sensitive probes mag-fura-2 and fura-2. There was a significant rise in [Mg2+]i after a 5 min exposure to a s...

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Veröffentlicht in:	Molecular and cellular biochemistry 1999-08, Vol.198 (1-2), p.129-133
Hauptverfasser:	Gow, I F, Flatman, P W, Ellis, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding sites Fluorescence Heart Ventricles - cytology Heart Ventricles - drug effects Heart Ventricles - metabolism Lithium Lithium - pharmacology Magnesium Magnesium - metabolism Male Rats Rats, Sprague-Dawley Sodium
Online-Zugang:	Volltext
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