Human neuronal gamma-aminobutyric acid(A) receptors: coordinated subunit mRNA expression and functional correlates in individual dentate granule cells

gamma-Aminobutyric acid(A) receptors (GABARs) are heteromeric proteins composed of multiple subunits. Numerous subunit subtypes are expressed in individual neurons, which assemble in specific preferred GABAR configurations. Little is known, however, about the coordination of subunit expression withi...

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Veröffentlicht in:	The Journal of neuroscience 1999-10, Vol.19 (19), p.8312-8318
Hauptverfasser:	Brooks-Kayal, A R, Shumate, M D, Jin, H, Lin, D D, Rikhter, T Y, Holloway, K L, Coulter, D A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Cells, Cultured Clonazepam - pharmacology Dentate Gyrus - metabolism Dentate Gyrus - pathology Epilepsy - genetics Epilepsy - surgery Female Gene Expression Regulation - drug effects Hippocampus - surgery Humans Kinetics Macromolecular Substances Male Middle Aged Neurons - drug effects Neurons - metabolism Neurons - physiology Patch-Clamp Techniques Rats Receptors, GABA-A - genetics Receptors, GABA-A - physiology RNA, Antisense - genetics RNA, Messenger - genetics Transcription, Genetic - drug effects
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