The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development

Cell migration during embryonic tracheal system development in Drosophila requires DPP and EGF signaling to generate the archetypal branching pattern. We show that two genes encoding the transcription factors KNIRPS and KNIRPS RELATED possess multiple and redundant functions during tracheal developm...

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Veröffentlicht in:	Development (Cambridge) 1998-12, Vol.125 (24), p.4959-4968
Hauptverfasser:	Chen, Chao-Kung, Kühnlein, Ronald P., Eulenberg, Karsten G., Vincent, Stéphane, Affolter, Markus, Schuh, Reinhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement - physiology DNA-Binding Proteins - metabolism Drosophila Drosophila - embryology Drosophila - growth & development Drosophila Proteins Epidermal Growth Factor - metabolism Fibroblast Growth Factors - metabolism Gene Expression Regulation, Developmental - genetics Genes, Reporter - genetics Homeodomain Proteins - metabolism Immunohistochemistry In Situ Hybridization Insect Proteins - metabolism Morphogenesis - physiology Repressor Proteins - metabolism Signal Transduction - physiology Trachea - growth & development Transcription Factors - metabolism
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