Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis

Background: Virulence in the pathogenic bacterium Yersinia pestis, causative agent of bubonic plague, has been correlated with the biosynthesis and transport of an iron-chelating siderophore, yersiniabactin, which is induced under iron-starvation conditions. Initial DNA sequencing suggested that thi...

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