Osteocalcin: Genetic and Physical Mapping of the Human Gene BGLAP and Its Potential Role in Postmenopausal Osteoporosis

Osteocalcin is an abundant, highly conserved bone-specific protein that is synthesized by osteoblasts. Temporally, osteocalcin appears in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. A role for osteocalcin in bone resorption has be...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1999-09, Vol.60 (2), p.210-217
Hauptverfasser:	Raymond, Michael H., Schutte, Brian C., Torner, James C., Burns, Trudy L., Willing, Marcia C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alleles Base Sequence Biological and medical sciences Bone Density - genetics Case-Control Studies Chromosome Mapping Chromosomes, Human, Pair 1 - genetics Classical genetics, quantitative genetics, hybrids Diseases of the osteoarticular system DNA Primers - genetics Female Fundamental and applied biological sciences. Psychology Genetic Variation Genetics of eukaryotes. Biological and molecular evolution Human Humans Linkage Disequilibrium Medical sciences Microsatellite Repeats Middle Aged Osteocalcin - genetics Osteoporosis, Postmenopausal - genetics Osteoporosis. Osteomalacia. Paget disease Physical Chromosome Mapping
Online-Zugang:	Volltext
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