IL-10 Inhibits Porphyromonas gingivalis LPS-Stimulated Human Gingival Fibroblasts Production of IL-6

Lipopolysaccharides (LPS) of Porphyromonas gingivalis have been implicated in the initiation and development of periodontal diseases. In a previous study, we investigated the signal transduction pathway of P. gingivalis and demonstrated that LPS stimulates the production of interleukin (IL)-6 in hum...

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Veröffentlicht in:	Biochemical and biophysical research communications 1999-09, Vol.263 (2), p.372-377
Hauptverfasser:	Wang, Pao-Li, Shirasu, Shinya, Shinohar, Mitsuko, Azuma, Yasutaka, Daito, Michiharu, Yasuda, Hideki, Ohura, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Fibroblasts - cytology Fibroblasts - immunology Gingiva - cytology Gingiva - immunology human gingival fibroblasts Humans IL-10 Interleukin-10 - pharmacology Interleukin-6 - biosynthesis Lipopolysaccharides - immunology LPS periodontal diseases Periodontal Diseases - etiology Phosphorylation Porphyromonas gingivalis Porphyromonas gingivalis - immunology Protein-Tyrosine Kinases - metabolism
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