Hematopoietic, immunomodulatory and epithelial effects of interleukin-11

Interleukin 11 (IL-11) is a pleiotropic cytokine with biological activities on many different cell types. Recombinant human IL-11 (rhIL-11) is produced by recombinant DNA technology in Escherichia coli. Both in vitro and in vivo, rhIL-11 has shown effects on multiple hematopoietic cell types. Its pr...

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Veröffentlicht in:	Leukemia 1999-09, Vol.13 (9), p.1307-1315
Hauptverfasser:	SCHWERTSCHLAG, U. S, TREPICCHIO, W. L, DYKSTRA, K. H, KEITH, J. C, TURNER, K. J, DORNER, A. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute phase proteins Acute-Phase Reaction Adjuvants, Immunologic - pharmacology Analysis of the immune response. Humoral and cellular immunity Animal models Animals Arthritis Biological and medical sciences Biopsy C-reactive protein CD4 antigen Cell differentiation Chemotherapy Crohn's disease Cytokines Deoxyribonucleic acid Disease DNA E coli Endotoxemia Epithelium Epithelium - drug effects Ferritin Fibrinogen Fundamental and applied biological sciences. Psychology Fundamental immunology Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Growth factors Health services Hematopoiesis - drug effects Hemopoiesis Humans Immunobiology In vivo methods and tests Inflammatory bowel diseases Interleukin 11 Interleukin 12 Interleukin 6 Interleukin-11 - genetics Interleukin-11 - pharmacology Interleukin-11 Receptor alpha Subunit Joint diseases Kidneys Lymphocytes Lymphocytes T Lymphokines, interleukins ( function, expression) Macrophages Medical sciences Mucosa NF-^KB protein Nitric oxide Other diseases. Semiology Patients Proteins Psoriasis Receptors, Interleukin - genetics Receptors, Interleukin-11 Recombinant Proteins - pharmacology Regulatory factors and their cellular receptors Rheumatoid arthritis Skin diseases Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Translocation
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