ELISA methods for the analysis of antibody responses induced in multiple sclerosis patients treated with recombinant interferon-β

Upon treatment with protein therapeutics, a subset of patients will typically develop antibodies against the drug. These anti-drug antibodies can be of concern because they have the potential to alter the drug's therapeutic activity. In the case of relapsing-remitting multiple sclerosis (RRMS)...

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Veröffentlicht in:Journal of immunological methods 1999-07, Vol.227 (1), p.121-135
Hauptverfasser: Brickelmaier, Margot, Hochman, Paula S, Baciu, Rem, Chao, Betty, Cuervo, Julio H, Whitty, Adrian
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Sprache:eng
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