Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine

Although most viral vaccines used in humans have been composed of live attenuated viruses or whole killed viral particles, the latter approach has received little attention in research on experimental primate immunodeficiency virus vaccines. Inactivation procedures involving heat or formalin appear...

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Veröffentlicht in:	AIDS research and human retroviruses 1998-10, Vol.14 Suppl 3, p.S311-S319
Hauptverfasser:	Arthur, L O, Bess, Jr, J W, Chertova, E N, Rossio, J L, Esser, M T, Benveniste, R E, Henderson, L E, Lifson, J D
Format:	Artikel
Sprache:	eng
Schlagworte:	2,2'-Dipyridyl - analogs & derivatives 2,2'-Dipyridyl - pharmacology AIDS/HIV Antiviral Agents - pharmacology Cell Fusion Cell Line Chromatography, High Pressure Liquid Disulfides - pharmacology HIV-1 - isolation & purification HIV-1 - pathogenicity Human immunodeficiency virus 1 Humans Nucleocapsid Proteins - metabolism Simian immunodeficiency virus Simian Immunodeficiency Virus - drug effects Simian Immunodeficiency Virus - immunology Simian Immunodeficiency Virus - isolation & purification Temperature Viral Vaccines Virulence - immunology Zinc Fingers
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