Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation

Two subtypes of G-protein-coupled cannabinoid receptors have been identified to date: the CB1 central receptor subtype, which is mainly expressed in the brain, and the CB2 peripheral receptor subtype, which appears particularly abundant in the immune system. We investigated the expression of CB2 rec...

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Veröffentlicht in:	Blood 1998-11, Vol.92 (10), p.3605-3615
Hauptverfasser:	CARAYON, P, MARCHAND, J, LE FUR, G, DEFRANCE, T, CASELLAS, P, DUSSOSSOY, D, DEROCQ, J.-M, JBILO, O, BORD, A, BOUABOULA, M, GALIEGUE, S, MONDIERE, P, PENARIER, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocyte Subsets - cytology B-Lymphocyte Subsets - metabolism Biological and medical sciences Camphanes - pharmacology CD40 Antigens - physiology Cell Differentiation CHO Cells Cricetinae Cricetulus Cyclohexanols - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Germinal Center - cytology Humans Immunobiology Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Microscopy, Confocal Palatine Tonsil - cytology Peptide Fragments - immunology Piperidines - pharmacology Pyrazoles - pharmacology Rabbits Receptors, Cannabinoid Receptors, Drug - drug effects Receptors, Drug - genetics Receptors, Drug - immunology Receptors, Drug - physiology Recombinant Fusion Proteins - physiology Rimonabant Transfection
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