Proinflammatory cytokines regulate myogenic cell proliferation and fusion but have no impact on myotube protein metabolism or stress protein expression

The objective of the present study was to evaluate the effect of the proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha) and interleukin-1-alpha (IL-1a), on myoblast proliferation and fusion and on myocyte protein metabolism and stress protein expression. Proliferation was suppressed...

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Veröffentlicht in:	Journal of interferon & cytokine research 1998-10, Vol.18 (10), p.879-888
Hauptverfasser:	Ji, S Q, Neustrom, S, Willis, G M, Spurlock, M E
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division - drug effects Cell Fusion - drug effects Heat-Shock Proteins - biosynthesis Humans Interleukin-1 - pharmacology Muscle Proteins - metabolism Myogenic Regulatory Factors - pharmacology Recombinant Proteins - pharmacology Tumor Necrosis Factor-alpha - pharmacology
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